Friday, September 19, 2014
YOLO COUNTY NEWS
99 CENTS

Brain monitoring shows memory at work

Diagram of locations in the brain monitored by electrodes in some of Dr. Tandon's patients, also being used for research into memory by Arne Ekstrom at the UC Davis Center for Neuroscience. Courtesy graphic

By
From page A1 | January 31, 2013 |

Working with patients with electrodes implanted in their brains, researchers at UC Davis and the University of Texas Health Science Center at Houston have shown for the first time that areas of the brain work together at the same time to recall memories.

The unique approach promises new insights into how we remember details of time and place.

“Previous work has focused on one region of the brain at a time,” said Arne Ekstrom, assistant professor at the UCD Center for Neuroscience. “Our results show that memory recall involves simultaneous activity across brain regions.

Ekstrom is senior author of a paper describing the work published Jan. 27 in the journal Nature Neuroscience.

Ekstrom and UCD graduate student Andrew Watrous worked with patients being treated for a severe seizure condition by neurosurgeon Nitin Tandon and his UTHealth colleagues.

To pinpoint the origin of the seizures in these patients, Tandon and his team place electrodes on the patient’s brain inside the skull. The electrodes remain in place for one to two weeks for monitoring.

Six such patients volunteered for Ekstrom and Watrous’ study while the electrodes were in place. Using a laptop computer, the patients learned to navigate a route through a virtual streetscape, picking up passengers and taking them to specific places. Later, they were asked to recall the routes from memory.

Correct memory recall was associated with increased activity across multiple connected brain regions at the same time, Ekstrom said, rather than activity in one region followed by another.

However, the analysis did show that the medial temporal lobe is an important hub of the memory network, confirming earlier studies, he said.

Intriguingly, memories of time and of place were associated with different frequencies of brain activity across the network. For example, recalling, “What shop is next to the doughnut shop?” set off a different frequency of activity from recalling “Where was I at 11 a.m.?”

Using different frequencies could explain how the brain codes and recalls elements of past events such as time and location at the same time, Ekstrom said.

“Just as cell phones and wireless devices work at different radio frequencies for different information, the brain resonates at different frequencies for spatial and temporal information,” he said.

The researchers hope to explore further how the brain codes information in future work.

The neuroscientists analyzed their results with graph theory, a new technique that is being used for studying networks, ranging from social media connections to airline schedules.

“Previously, we didn’t have enough data from different brain regions to use graph theory. This combination of multiple readings during memory retrieval and graph theory is unique,” Ekstrom said.

Placing electrodes inside the skull provides clearer resolution of electrical signals than external electrodes, making the data invaluable for the study of cognitive functions, Tandon said. “This work has yielded important insights into the normal mechanisms underpinning recall, and provides us with a framework for the study of memory dysfunction in the future.”

— UC Davis News Service

Comments

comments

.

News

Grant means new push for moving tracks out of town

By Dave Ryan | From Page: A1 | Gallery

 
Some say council needs to reconsider MRAP

By Dave Ryan | From Page: A1

UC to create $250 million venture capital fund

By San Francisco Chronicle | From Page: A1

 
School district may redevelop downtown site

By Jeff Hudson | From Page: A1

 
Master Gardeners share their wisdom at free workshops

By Enterprise staff | From Page: A2

Scots vote to stay in UK

By The Associated Press | From Page: A2

 
France strikes Islamic State group’s depot in Iraq

By The Associated Press | From Page: A2

Man faces arson charge in huge California wildfire

By The Associated Press | From Page: A2

 
DUI suspected in crash

By Lauren Keene | From Page: A2

Woodland Healthcare offering flu shots

By Enterprise staff | From Page: A3

 
Storyteller will draw on music, dance

By Enterprise staff | From Page: A3

 
Putah Creek Bike Path to close temporarily

By Enterprise staff | From Page: A3

Little Free Libraries open at Montgomery

By Anne Ternus-Bellamy | From Page: A3

 
Project Linus seeks donations

By Enterprise staff | From Page: A3

Rabid bat found at Holmes Junior High

By Enterprise staff | From Page: A3

 
Students invited to apply for Blue & White grants

By Enterprise staff | From Page: A3

Telling tales, on ‘Davisville’

By Enterprise staff | From Page: A3

 
Halloween costume sale benefits preschool

By Enterprise staff | From Page: A3

Volunteers sought to make veggie bags

By Enterprise staff | From Page: A3

 
Register to vote by Oct. 20

By Enterprise staff | From Page: A4

Free workout class set at library

By Special to The Enterprise | From Page: A4

 
Explorit: Lots of ways to be a volunteer

By Lisa Justice | From Page: A4 | Gallery

 
Sierra Club remembers longtime walker

By Special to The Enterprise | From Page: A4

DHS Classes of 1954 and 1955 will hold 60th reunion

By Enterprise staff | From Page: A4

 
Nonprofits can get DCN’s help

By Enterprise staff | From Page: A4

Davis maps available at Chamber office

By Enterprise staff | From Page: A5

 
Need a new best friend?

By Enterprise staff | From Page: A5 | Gallery

Reception benefits endangered gorillas

By Special to The Enterprise | From Page: A5

 
Downtown history tour planned in October

By Enterprise staff | From Page: A7

Wolk applauds approval of stronger rules for olive oil

By Special to The Enterprise | From Page: A8

 
Davis hosts its own climate change rally

By Special to The Enterprise | From Page: A8

Sutter Farmers Market offers local goods

By Enterprise staff | From Page: A8 | Gallery

 
Qigong classes available for heart health

By Enterprise staff | From Page: A9

.

Forum

Sick of being the bad guy

By Creators Syndicate | From Page: B5

 
Cheers and Jeers: Not the end of the rainbow

By Our View | From Page: A6

Tom Meyer cartoon

By Debbie Davis | From Page: A6

 
Return to previous plan

By Letters to the Editor | From Page: A6

Save the ‘pine cone place’

By Letters to the Editor | From Page: A6

 
Affirm our community values

By Letters to the Editor | From Page: A6

Project has safety risks

By Letters to the Editor | From Page: A6

 
Learn more about Paso Fino

By Letters to the Editor | From Page: A6

Educate homeless with dogs

By Letters to the Editor | From Page: A6, 1 Comment

 
.

Sports

Aggies’ new energy could be scary for Big West

By Bruce Gallaudet | From Page: B1

 
No rest for the weary: Aggie TE Martindale busy on and off the field

By Bruce Gallaudet | From Page: B1 | Gallery

Devils hope the light bulb turns on at Edison

By Enterprise staff | From Page: B1

 
River Cats and Giants sign two-year deal

By Enterprise staff | From Page: B1

Blue Devil volleyballers hold off Herd

By Spencer Ault | From Page: B1 | Gallery

 
Take Zona and Bama this week

By Bob Dunning | From Page: B2

Mustangs are no match for DHS boys in water polo

By Enterprise staff | From Page: B2

 
A’s slide continues as Rangers sweep

By The Associated Press | From Page: B8

.

Features

Name Droppers: Awards keep coming for UC Davis retiree

By Enterprise staff | From Page: A7

 
.

Business

Redesigned 2015 Escalade remains breed all its own

By Ann M. Job | From Page: B3 | Gallery

 
.

Obituaries

.

Comics

Comics: Friday, September 19, 2014

By Creator | From Page: A10

 
.

Real Estate Review

Featured Listing

By Zack Snow | From Page: RER1

Professional Services Directory

By Zack Snow | From Page: RER2

Taylor Morrison

By Zack Snow | From Page: RER3

Malek Baroody

By Zack Snow | From Page: RER4

Norcal Land

By Zack Snow | From Page: RER5

Robin Garland

By Zack Snow | From Page: RER6

Karen Waggoner

By Zack Snow | From Page: RER7

Dana Hawkins

By Zack Snow | From Page: RER7

Martha Bernauer

By Zack Snow | From Page: RER8

Joe Kaplan

By Zack Snow | From Page: RER8

Lynne Wegner

By Zack Snow | From Page: RER8

Remax

By Zack Snow | From Page: RER9

Melrina A Maggiora

By Zack Snow | From Page: RER10

Wells Fargo Home Mortgage

By Zack Snow | From Page: RER11

Julie Leonard

By Zack Snow | From Page: RER11

Coldwell Banker

By Zack Snow | From Page: RER12

Kim Eichorn

By Zack Snow | From Page: RER14

Lyon Real Estate

By Zack Snow | From Page: RER15

Julie Partain

By Zack Snow | From Page: RER16

Jamie Madison & Associates

By Zack Snow | From Page: RER16

Marcelo Campos

By Zack Snow | From Page: RER16

Bob Bockwinkel

By Zack Snow | From Page: RER17

Juan Ramirez

By Zack Snow | From Page: RER17

Kim Merrel Lamb

By Zack Snow | From Page: RER17

Chris Snow

By Zack Snow | From Page: RER18

James Hanna

By Zack Snow | From Page: RER18

Raul Zamora

By Zack Snow | From Page: RER19

Susan von Geldern

By Zack Snow | From Page: RER19

Travis Credit Union

By Zack Snow | From Page: RER20

Jamie Madison

By Zack Snow | From Page: RER21

Karen Waggoner

By Zack Snow | From Page: RER21

Lisa Haass

By Zack Snow | From Page: RER22

Tracy Harris

By Zack Snow | From Page: RER22

First Street Real Estate

By Zack Snow | From Page: RER24