Wednesday, October 1, 2014
YOLO COUNTY NEWS
99 CENTS

Wheat geneticists work to decode massive genome

By
From page A4 | October 23, 2013 |

An international effort aimed at sequencing a wheat ancestor’s genome — which is 40 percent larger than the human genome — is being led by UC Davis scientists.

The project, recently funded by a $9 million grant from the National Science Foundation’s Plant Genome Research project, is focused on better understanding the genetics of bread wheat, one of three cereals that provide most of the world’s food. Bread wheat also has the distinction of having a genome that consists of three genomes from separate species, each with a complexity and size that make genetic decoding exceptionally difficult.

The project will sequence the genome of the goatgrass Aegilops tauschii, a wild relative of common bread wheat that is responsible for the bread-making quality found in wheat. It also is highly tolerant of salt, drought, aluminum, frost, pests and many wheat diseases.

In studying the Ae. tauschii genome, scientists plan to identify the genes controlling the important environmental tolerance and resistance traits, and gain a finer understanding of the biological causes behind the enormous sizes of many plant genomes. The Ae. tauschii code also will provide geneticists with a badly needed reference for wheat genomics and sequence assembly.

The effort already has produced its first practical outcome: the discovery of a gene with a resistance to wheat stem rust, recently published as a cover article in the journal Science.

Geneticists previously had hoped to decode the wheat and Ae. tauschii genomes using the shotgun sequencing approach, which is like piecing together a book from millions of random sentence fragments. The team, instead, is using an approach known as “ordered clone sequencing” to generate a high-quality blueprint of the Ae. tauschii genome, along with nanomapping, which traps DNA molecules in nano-sized channels where their unique pattern is visualized and quantified.

“This is really an exciting technology,” said Jan Dvorak, a lead scientist on the team, as well as a UCD professor and geneticist. “For the first time in genome sequencing, we have an independent means to check the accuracy of the genome sequence assembly and correct errors and fill gaps.”

Ming-Cheng Luo, a co-investigator and UCD geneticist, worked with BioNano Genomics, the manufacturer of the sequencing instrument, to adapt the technology to ordered clone sequencing.

“This technology will now be available to all the genomic programs in the campus community,” Luo said.

The genome project is a partnership between UCD and a number of U.S. and Chinese institutions, with additional support from the Chinese Wheat Genome Working Group. Several visiting scientists and students also are involved with the project.

Other co-investigators include Yong Qiang Gu and Olin Anderson of UCD/USDA-ARS, Katrien Devos of the University of Georgia and Steven Salzberg of Johns Hopkins University.

— UC Davis News Service

Comments

comments

.

News

Sanity phase begins in Daniel Marsh trial

By Lauren Keene | From Page: A1

 
Council looks at granny-flat revision

By Dave Ryan | From Page: A1

Man on a mission: transform Davis

By Dave Ryan | From Page: A1 | Gallery

 
Poppenga outlines ambitious agenda

By Jeff Hudson | From Page: A1 | Gallery

Cool Davis Festival is très chill

By Special to The Enterprise | From Page: A1 | Gallery

 
Standing In: Is the therapy for them, or me?

By Special to The Enterprise | From Page: A2

California exhausts initial firefighting budget

By The Associated Press | From Page: A2

 
Brown allows new local development financing tools

By The Associated Press | From Page: A2

Find the perfect club or organization to join

By Enterprise staff | From Page: C2 | Gallery

 
California becomes first state to ban plastic bags

By The Associated Press | From Page: A2

 
Forum examines Props. 1 and 2 on November ballot

By Enterprise staff | From Page: A3

Assembly candidates will be at Woodland forum

By Enterprise staff | From Page: A4

 
Pets of the week

By Enterprise staff | From Page: A4 | Gallery

California approves landmark ‘yes means yes’ law

By The Associated Press | From Page: A4

 
Try out basic yoga on Thursday

By Enterprise staff | From Page: A4

DCC welcomes students with free lunch

By Enterprise staff | From Page: A4

 
Gibson House hosts plant sale and garden event

By Special to The Enterprise | From Page: A4

Register to vote by Oct. 20

By Enterprise staff | From Page: A4

 
Covell Gardens breakfast benefits Komen Foundation

By Enterprise staff | From Page: A5

 
Put your hoes down and celebrate the harvest

By Special to The Enterprise | From Page: A5 | Gallery

Panelists discuss raising children with special needs

By Special to The Enterprise | From Page: A5

 
DCC hosts fair-trade gift sale on Oct. 11

By Enterprise staff | From Page: A5

Number of wheels: How many bicycles do you have in your household?

By Enterprise staff | From Page: C5 | Gallery

 
Emerson gives away old textbooks

By Special to The Enterprise | From Page: A5

Downtown history tour planned in October

By Enterprise staff | From Page: A5

 
Fraud Awareness Fair set Oct. 15 in West Sac

By Enterprise staff | From Page: A5

UCD, University College Dublin will cooperate on food, health

By Special to The Enterprise | From Page: A5

 
Accessibility technology on exhibit at fair

By Enterprise staff | From Page: A5

 
Woodland PD seeks volunteers for ViP program

By Special to The Enterprise | From Page: A7

DMTC makes musical theater accessible to everyone

By Bev Sykes | From Page: C9 | Gallery

 
Take home a wreath from Davis Flower Arrangers’ meeting

By Special to The Enterprise | From Page: A10

Snapshot: A night out with the neighbors

By Enterprise staff | From Page: C10

 
Davis school names reflect interesting history

By Jeff Hudson | From Page: C12

Snapshot: Plenty of places to park it

By Enterprise staff | From Page: C14

 
Snapshot: Dive into Davis fun

By Enterprise staff | From Page: C15

Snapshot: Kick garbage to the curb

By Enterprise staff | From Page: C16

 
Snapshot: Sounds like a party

By Enterprise staff | From Page: C17

.

Forum

It takes two to lambada

By Creators Syndicate | From Page: B5

 
He seems happy at home

By Creators Syndicate | From Page: B5

The great bedtime conspiracy

By Letters to the Editor | From Page: A6

 
They’re best-prepared to lead

By Letters to the Editor | From Page: A6

Vibrant and hard-working

By Letters to the Editor | From Page: A6

 
Archer has the right stuff

By Letters to the Editor | From Page: A6

Tom Meyer cartoon

By Debbie Davis | From Page: A6

 
Get on your bikes to meet Davis’ greenhouse gas goals

By Special to The Enterprise | From Page: A6

Marsh case shows need for ‘Maupin’s Law’

By Special to The Enterprise | From Page: A6

 
.

Sports

Only 15 months out of UCD, Runas off to LPGA Tour

By Bruce Gallaudet | From Page: B1 | Gallery

 
Davis golfers get teaching moments in forfeit win

By Enterprise staff | From Page: B1

‘Playoff game’ or missed chance? Either way the Aggies move on

By Bruce Gallaudet | From Page: B1 | Gallery

 
Devils move atop league standings with win

By Evan Ream | From Page: B1 | Gallery

 
Two Junior Blue Devil squads emerge victorious

By Enterprise staff | From Page: B2

 
.

Features

.

Arts

 
Woodland artist hosts event at her new studio

By Enterprise staff | From Page: A9

I-House film series continues with ‘Monsieur Lazhar’

By Enterprise staff | From Page: A9

 
‘Art Farm’ exhibition will open in Woodland

By Enterprise staff | From Page: A9

Pleasant Valley Boys cool down Picnic in the Park

By Special to The Enterprise | From Page: A9 | Gallery

 
Acclaimed guitarist Peppino D’Agostino to play The Palms

By Landon Christensen | From Page: A9

.

Business

.

Obituaries

Danelle Evelyn Watson

By Special to The Enterprise | From Page: A4

 
Michael Allen Hanks Baxter

By Special to The Enterprise | From Page: A4

Anne Elizabeth Elbrecht

By Special to The Enterprise | From Page: A4

 
.

Comics

Comics: Tuesday, September 30, 2014 (set 1)

By Creator | From Page: B5

 
Comics: Tuesday, September 30, 2014 (set 2)

By Creator | From Page: B7